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Posts with tag cholesterol drug

Vytorin debate continues

Posted: Mar 31st 2008 12:30PM by Maggie Vink
Filed under: General Health, Health in the Media

A medication frequently prescribed for high cholesterol came under fire a few months ago when a trial showed the medication -- a combination of simvastin and ezetimibe -- worked no better than simvastin alone. Simvastin is a statin designed to lower LDL cholesterol; ezetimibe is another medication that should lower LDL in another way.

The results of the trials regarding the efficacy of Vytorin are being discussed at the American College of Cardiology's annual meeting this week. At this point, researchers aren't entirely sure if the results of the trial are indicative of how Vytorin would affect those with mildly high cholesterol or those who are newly diagnosed; all the participants in the study had very high cholesterol and had been under treatment for years.

Merck's Mevacor cholesterol drug to go over the counter soon?

Posted: Dec 13th 2007 7:37AM by Brian White
Filed under: Health in the Media

It's interesting to see that Merck, the pharmaceutical giant, wants to make its Mevacor cholesterol-lowering drug available as an over-the-counter drug, but that is precisely what is happening.

However, the FDA wonders if making the drug available to anyone who wants it will lead to many patients taking the drug who really do not need it.

It's hard to imagine folks without high cholesterol problems seeking our Mevacor at the local Wal-Mart, but of course this would happen in an age of "fix this" medicines and instant gratification health environments.

Case in point -- only 20 percent of potential patients interviewed by Merck answered all questions correctly when quizzed about proper usage of Mevacor.

Study says to keep using statins after stroke happens

Posted: Aug 28th 2007 4:00PM by Brian White
Filed under: Health and Technology

In a new study that seems more like an advertisement than fact (to me, anyway), the risk of death or complete dependency 90 days after a stroke happens was enhanced if statin drugs were not kept on a patient's drug menu.

Since statin drugs are relatively new in terms of actual pharmaceutical products, the results of this study seem to suggest that statin drugs, generally used to lower 'bad' cholesterol, are now helpful in treating stroke victims.

Perhaps statin drugs do in fact help the brain continue to receive oxygen in the event of a stroke, but without seeing the actual results of several clinical studies that suggested (but apparently did not prove) this result, I remain skeptical.

Pfizer sues to block generic cholesterol drug from being sold

Posted: Mar 13th 2007 8:32PM by Brian White
Filed under: General Health

I guess it makes good business sense for consumer health care and large pharmaceutical firms to protect the patents and profits on drugs that they spent millions to develop -- but where does one draw the line?

Pharmaceutical giant Pfizer -- who is the world's biggest drugmaker -- has made the point pretty clear by suing Ranbaxy Laboratories so that the latter company will not market a generic version of the cholesterol and blood pressure medicine Caduet (which is made by Pfizer).

Ranbaxy, based in India, wants FDA approval to sell a "cheaper version" of Caduet. Pfizer almost immediately called in the patent law team, stating that such a drug would infringe on two patents granted to Pfizer that expire in 2010 and 2018.

Cholestrol drug trial results found "not significant"

Posted: Mar 10th 2007 11:58AM by Brian White
Filed under: Health and Technology

Although newer pharmaceutical drugs have been hailed as killers by some and lifesavers by others, there is no doubt many of these come with undesirable side effects. With cholesterol on the minds of many these days, drugs to keep that under control are being prescribed in rising numbers.

But one won't make it to the public at all, as clinical trial results for a new Canadian cholesterol management product showed that its use had "no statistically significant" effect. Ouch.

Possible variables remain on the trial's results, as the study of the drug CRD5 was done over the Christmas season. During that time, heavier than normal alcohol amounts were consumed -- possibly affecting results, according to Liponex, the drug's manufacturer.



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