I had a roommate in college that had what we called "jimmy legs." She didn't know what was wrong, but as soon as she'd lay down to sleep her legs would start to feel "creepy crawly" (her words) and the next thing you'd know she'd be jerking and shaking her legs -- sometimes on purpose, sometimes not. We used to laugh it off, but I know it was really uncomfortable for her. And I know that, since she didn't know what was really going on, it was frightening for her, too.

Though I can't say for sure, my guess is that my roommate had restless leg syndrome (RLS). RLS is a neurological condition that affects up to 10% of the US population. RLS patients feel uncomfortable sensations and an overwhelming urge to move their legs. Symptoms become worse during rest -- particularly when lying down -- and are put at bay by movement.

GlaxoSmithKline's Requip medication has been a premiere treatment for mild to moderate RLS. The FDA just approved a generic form of Requip. The medication is also approved to treat symptoms of Parkinson's Disease.