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Molecule in brain gives hope for PTSD cure

Posted on Jul 16th 2007 10:00PM by Maggie Vink
Filed Under: Motivation
I adopted my son from the foster care system. He suffers from post-traumatic stress disorder due to events that occurred before he entered foster care. PTSD bleeds into so many areas of his life now -- for example, he has a hair-trigger response to fear; little noises or other things that wouldn't even startle most people shake him to the core. Childhood trauma isn't the only cause of PTSD -- any traumatic event can leave someone with some or all of the symptoms. In a nutshell, PTSD is created when the brain is unable to stop replaying events or experiencing the fear and other emotions associated with a significant traumatic event or time period.

Other than therapy and antidepressants, there is no standard treatment for PTSD at this time. A current study blocked an enzyme called Cdk5 in the brains of mice that had been given mild foot shocks. Mice who had received the foot shock, but hadn't had the enzyme blocked, exhibited symptoms of fear when put in the same environment where they had been previously shocked. Mice who had Cdk5 blocked, didn't exhibit fear symptoms.

The research is preliminary and is a long way from being applicable to humans, but it does give hope that someday there may be a treatment for PTSD.

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